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Regardless of drinking and smoking, men are much more sensitive to head and neck cancer than women, and men also have a much higher incidence rate.

Professor Park Joon-wook, Professor Lee Dong-hyun of the Head and Neck Cancer Center of Eunpyeong St. Mary's Hospital, 미수다알바 and Professor Joo Young-hoon of Bucheon St. Mary's Hospital conducted the first 10-year follow-up cohort study comparing the incidence of head and neck cancer of healthy men to women in 2009.

According to the research team's follow-up observation, a total of 17,732 people were newly diagnosed with head and neck cancer for 10 years from 2010 to 2019, and 0.25 people per 1,000 people had head and neck cancer. Among them, men had a higher incidence rate than 0.06 women at 0.19 per 1,000 people.

By cancer type, the difference between men and women in larynx cancer was the most pronounced, and men in their 40s had 11 times higher incidence of larynx cancer than women and 20 times higher in their 60s. In the case of Heindu cancer, men in their 40s were 6.8 times higher and men in their 60s were 24.2 times higher, with a stark difference in incidence between women and men.

Considering that men smoke and drink more than women, the incidence of head and neck cancer in men is 2.9 times higher than that of women, indicating that men are much more sensitive to head and neck cancer regardless of smoking and drinking.

In terms of age-specific characteristics, the gender difference in the incidence of head and neck cancer changed based on the age of 70. By the age of 70, there was a large difference in incidence between men and women, especially in their late 60s, and after that, the difference gradually decreased.

In addition, the risk of head and neck cancer in men compared to women tended to be significantly higher in the larynx and lower head areas than in the mouth and mouth, and there was no gender difference only in the case of salivary gland cancer.

Head and neck cancer refers to cancer that occurs in all parts of the head and neck except the brain and eyes, and is known to have the sixth highest incidence rate worldwide and 700,000 patients every year. Until now, there have been reports that men are more vulnerable to head and neck cancer than women epidemiologically, but most of them have been based on fragmentary data, and no analysis has been conducted through large-scale cohort studies.

Park Joon-wook, a professor at the Head and Neck Cancer Center at Eunpyeong St. Mary's Hospital, said, "This study is the first long-term follow-up study based on the nation's population, and it is very meaningful in that it identified the incidence of head and neck cancer patients in Korea for the first time."

Professor Lee Dong-hyun said, "We expect that further research on head and neck cancer in the future will be of great help in establishing a systematic treatment strategy based on epidemiological data by gender and age obtained through the study."

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